I had a severe bout of clinical depression along with my anxiety/panic disorder about two years ago. I am extremely sensative to medications, so it has always been a struggle to find something that works. Most cause weight gain, which makes my condition worse as this is a stressor. Effexor made my legs feel like they were going to fall off. As for Zoloft - that really helped me. I took it for six months, weaning as we got toward the end and it worked wonders. It gets my vote. I also take Xanax .025 every night at bedtime. Have for 18 years. My doc told me back then that I had to treat my disorder just like a diabetic would treat his condition, so I continue to take it just to keep it in my system (barely, I know) in case I need to step it up. :p
