I believe that PA's DO run in families! I have several relatives (all on my mothers' side of the family gene pool) that suffer from anxiety. Unfortunately for me, I seem to suffer the worst with it. And, oddly enough, as far as I know, I'm the only male that has it. There are also some other similarities in the family ( I'm not gonna mention, so everyone who reads this will panic over yet another symptom!) Bottom line, I truly believe this is a genetic condition. In fact, Columbia University in New York State is currently doing a study on the genetic aspect of anxiety. If you would like more info, e-mail me jjmosher@yahoo.com and I'll send you the e-mail addy of the person in charge. Remember though, it's just a study in progress, there aren't any Yes or No answers! You may even be able to participate in the study if you're interested. HTH!!